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1

Aspirin, but not no-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation

John L. Wallace, Andrea Mencarelli, Piero Del Soldato, Stefano Fiorucci

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

2

Nitric Oxide-Releasing Drugs : A Novel Class of Effective and Safe Therapeutic Agents

JEAN-LUC BURGAUD, ENNIO ONGINI, PIERO DEL SOLDATO

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 145 KB

english, 2002

3

Therapeutic potential of new hydrogen sulfide-releasing hybrids

Sparatore, Anna, Santus, Giancarlo, Giustarini, Daniela, Rossi, Ranieri, Del Soldato, Piero

Journal:

Expert Review of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 599 KB

english, 2011

4

Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative

Ling Li, Giuseppe Rossoni, Anna Sparatore, Lin Chiou Lee, Piero Del Soldato, Philip Keith Moore

Journal:

Free Radical Biology and Medicine

Year:

2007

Language:

english

File:

PDF, 716 KB

english, 2007

5

21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties

Mark Paul-Clark, Piero Del Soldato, Stefano Fiorucci, Roderick J Flower, Mauro Perretti

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 219 KB

english, 2000

6

Inhibition of bone resorption in vitro and prevention of ovariectomy-induced bone loss in vivo by flurbiprofen nitroxybutylester (HCT1026)

Kenneth J. Armour, Robert J. Van 't Hof, Katharine E. Armour, Anne C. Torbergsen, Piero Del Soldato, Stuart H. Ralston

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 108 KB

english, 2001

7

New aryldithiolethione derivatives as potent histone deacetylase inhibitors

Valerio Tazzari, Graziella Cappelletti, Manolo Casagrande, Elena Perrino, Luigi Renzi, Piero Del Soldato, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 287 KB

english, 2010

8

NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver

Stefano Fiorucci, Elisabetta Antonelli, Vincenzo Brancaleone, Laura Sanpaolo, Stefano Orlandi, Eleonora Distrutti, Giancarlo Acuto, Carlo Clerici, Monia Baldoni, Piero Del Soldato, Antonio Morelli

Journal:

Journal of Hepatology

Year:

2003

Language:

english

File:

PDF, 335 KB

english, 2003

9

Effects on intestinal microflora, gastrointestinal tolerability and antiinflammatory efficacy of diclofenac and nitrofenac in adjuvant arthritic rats

Laura Cuzzolin, Anita Conforti, Marta Donini, Alessandra Adami, Piero Del Soldato, Giuseppina Benoni

Journal:

Pharmacological Research

Year:

1994

Language:

english

File:

PDF, 550 KB

english, 1994

10

NO-aspirin protects from T cell–mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines

Stefano Fiorucci, Luca Santucci, Elisabetta Antonelli, Eleonora Distrutti, Giuseppe del Sero, Olivia Morelli, Luigina Romani, Barbara Federici, Piero del Soldato, Antonio Morelli

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 908 KB

english, 2000

11

Effect of hydrogen sulphide-donating sildenafil (ACS6) on erectile function and oxidative stress in rabbit isolated corpus cavernosum and in hypertensive rats

Nilima Shukla, Giuseppe Rossoni, Matthew Hotston, Anna Sparatore, Piero Del Soldato, Valerio Tazzari, Raj Persad, Gianni D. Angelini, Jamie Y. Jeremy

Journal:

BJU International

Year:

2009

Language:

english

File:

PDF, 306 KB

english, 2009

12

NCX-1015, a novel nitric oxide-releasing derivative of prednisolone, but not prednisolone protects against ischemia-reperfusion damage induced by naproxen or rofecoxib in the rat stomach

Nadia Sawka, Piero Del Soldato, Brigitta M. Peskar

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 176 KB

english, 2003

13

Gastric lesion-preventing or -potentiating activity of clonidine in rats.

SOLDATO, Piero DEL

Journal:

The Japanese Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 166 KB

english, 1986

14

NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives

Paula Zacharowski, Emma Breese, Elizabeth Wood, Piero Del Soldato, Tim Warner, Jane Mitchell

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 268 KB

english, 2005

15

Comparison of the gastric cytoprotective properties of atropine, ranitidine and PGE2 in rats

Piero Del Soldato, Diego Foschi, Luisa Varin, Sergio Daniotti

Journal:

European Journal of Pharmacology

Year:

1984

Language:

english

File:

PDF, 353 KB

english, 1984

16

Nitric oxide-donating non-steroidal anti-inflammatory drugs: the case of nitroderivatives of aspirin

Valerio Chiroli, Francesca Benedini, Ennio Ongini, Piero Del Soldato

Journal:

European Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 228 KB

english, 2003

17

NO-mesalamine protects colonic epithelial cells against apoptotic damage induced by proinflammatory cytokines

Fiorucci, Stefano, Distrutti, Eleonora, Ajuebor, Maureen N., Mencarelli, Andrea, Mannucci, Roberta, Palazzetti, Barbara, Del Soldato, Piero, Morelli, Antonio, Wallace, John L.

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2001

Language:

english

File:

PDF, 855 KB

english, 2001

18

New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity

Elena Perrino, Graziella Cappelletti, Valerio Tazzari, Erminio Giavini, Piero Del Soldato, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

19

New prostaglandin derivative for glaucoma treatment

Elena Perrino, Caterina Uliva, Cecilia Lanzi, Piero Del Soldato, Emanuela Masini, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

20

The therapeutic potential of NO-NSAIDs

John L. Wallace, Piero Del Soldato

Journal:

Fundamental & Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 159 KB

english, 2003

21

Enhanced anti-inflammatory effects of a nitric oxide–releasing derivative of mesalamine in rats

John L. Wallace, Nathalie Vergnolle, Marcelo N. Muscará, Samuel Asfaha, Kevin Chapman, Webb McKnight, Piero Del Soldato, Antonio Morelli, Stefano Fiorucci

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 230 KB

english, 1999

22

Nitric oxide-releasing non-steroidal anti-inflammatory drugs: a new generation of antithrombotics?

Wallace, John L, Soldato, Piero Del, Cirino, Giuseppe

Journal:

Expert Opinion on Investigational Drugs

Year:

1997

Language:

english

File:

PDF, 133 KB

english, 1997

23

Section Review: Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis: Development of NSAIDs with reduced gastrointestinal and renal toxicity

Wallace, John L., Del Soldato, Piero, Cirino, Giuseppe

Journal:

Expert Opinion on Investigational Drugs

Year:

1995

Language:

english

File:

PDF, 845 KB

english, 1995

24

The Effect of the New H2-Receptor Antagonist Mifentidine on Gastric Secretion, Gastric Emptying and Experimental Gastric and Duodenal Ulcers in the Rat: Comparison with Cimetidine and Ranitidine

Scarpignato, Carmelo, Tangwa, Martin, Tramacere, Roberto, Del Soldato, Piero

Journal:

Year:

1986

Language:

english

File:

PDF, 1.33 MB

english, 1986

25

Anti-inflammatory effects of nitric oxide-releasing hydrocortisone NCX 1022, in a murine model of contact dermatitis

Eric Hyun, Manlio Bolla, Martin Steinhoff, John L Wallace, Piero Del Soldato, Nathalie Vergnolle

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 247 KB

english, 2004

26

Comparison of the antinociceptive activity of two new NO-releasing derivatives of the NSAID S-ketoprofen in rats

Gema Gaitan, F Javier Ahuir, Piero Del Soldato, Juan F Herrero

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

27

Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons

Gary L Wenk, Kristin McGann, Andrea Mencarelli, Beatrice Hauss-Wegrzyniak, Piero Del Soldato, Stefano Fiorucci

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 666 KB

english, 2000

28

NO-aspirins: a class of new anti-inflammatory and antithrombotic agents

Piero del Soldato, Raffaella Sorrentino, Aldo Pinto

Journal:

Trends in Pharmacological Sciences

Year:

1999

Language:

english

File:

PDF, 227 KB

english, 1999

29

Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation

Wallace, John L., Zamuner, Stella R., McKnight, Webb, Dicay, Michael, Mencarelli, Andrea, del Soldato, Piero, Fiorucci, Stefano

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2004

Language:

english

File:

PDF, 168 KB

english, 2004

30

Nitric Oxide-Donating Non-Steroidal Antiinflammatory Drugs: The Case of Nitroderivatives of Aspirin.

Valerio Chiroli, Francesca Benedini, Ennio Ongini, Piero Del Soldato

Journal:

Year:

2003

File:

PDF, 120 KB

2003

31

Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice THIS ARTICLE HAS BEEN RETRACTED

Stefano Fiorucci, Elisabetta Antonelli, Eleonora Distrutti, Andrea Mencarelli, Silvana Farneti, Piero Del Soldato, Antonio Morelli

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 340 KB

english, 2004

32

Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of non-small cell lung cancer cells

Moody, Terry W., Switzer, Christopher, Santana-Flores, Wilmarie, Ridnour, Lisa A., Berna, Marc, Thill, Michelle, Jensen, Robert T., Sparatore, Anna, Del Soldato, Piero, Yeh, Grace C., Roberts, David D

Journal:

Year:

2010

Language:

english

File:

PDF, 754 KB

english, 2010

33

Organosulfur derivatives of the HDAC inhibitor valproic acid sensitize human lung cancer cell lines to apoptosis and to cisplatin cytotoxicity

Anna Tesei, Giovanni Brigliadori, Silvia Carloni, Francesco Fabbri, Paola Ulivi, Chiara Arienti, Anna Sparatore, Piero Del Soldato, Alice Pasini, Dino Amadori, Rosella Silvestrini, Wainer Zoli

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 474 KB

english, 2012

34

NO-donating aspirin inhibits intestinal carcinogenesis in Min (APCMin/+) mice

Jennie L Williams, Khosrow Kashfi, Nengtai Ouyang, Piero del Soldato, Levy Kopelovich, Basil Rigas

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 252 KB

english, 2004

35

Celecoxib exacerbates gastrointestinal damage induced by aspirin but not by no-aspirin (NCX-4016): A randomised, parallel group, blind-observer endoscopic study. Evidence for a protective role of no in the gastrointestinal mucosa

Stefano Fiorucci, Luca Santucci, Andrea Mencarelli, Eleonora Distrutti, Cinzia Fanini, Barbara Federici, Marco Sardina, Giancarlo Santus, John L. Wallace, Piero Del Soldato, Antomo Morelli

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

36

NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property?

Raymond K Yeh, Jie Chen, Jennie L Williams, Mehdi Baluch, Thomas R Hundley, Raphael E Rosenbaum, Srinivas Kalala, Frank Traganos, Francesca Benardini, Piero del Soldato, Khosrow Kashfi, Basil Rigas

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 261 KB

english, 2004

37

An NO-derivative of acetaminophen, NCX-701, spares the liver by inhibiting fasdependent apoptosis

Fiorucci, Stefano, Antonelli, Elisabetta, Mencarelli, Andrea, Palazzetti, Barbara, Del Soldato, Piero, Antipolis, Sophia, Morelli, Antonio

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 188 KB

english, 2001

38

Prevention of pulmonary thromboembolism by NCX 4016, a nitric oxide-releasing aspirin

Stefania Momi, Michael Emerson, William Paul, Mario Leone, Anna Maria Mezzasoma, Piero Del Soldato, Clive P Page, Paolo Gresele

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 313 KB

english, 2000

39

ACS84, a novel hydrogen sulfide-releasing compound, protects against amyloid β-induced cell cytotoxicity

Yan-Ying Liu, Anna Sparatore, Piero Del Soldato, Jin-Song Bian

Journal:

Neurochemistry International

Year:

2011

Language:

english

File:

PDF, 2.21 MB

english, 2011

40

Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma

Adrian W. Bak, Webb McKnight, Pamela Li, Piero Del Soldato, Antonio Calignano, Giuseppe Cirino, John L. Wallace

Journal:

Year:

1998

Language:

english

File:

PDF, 583 KB

english, 1998

41

Co-Administration of Nitric Oxide-Aspirin (NCX-4016) and Aspirin Prevents Platelet and Monocyte Activation and Protects Against Gastric Damage Induced by Aspirin in Humans

Stefano Fiorucci, Andrea Mencarelli, Alessandra Meneguzzi, Alessandro Lechi, Barbara Renga, Piero del Soldato, Antonio Morelli, Pietro Minuz

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 247 KB

english, 2004

42

Novel nitric oxide-releasing NSAID derivatives: Anti-inflammatory, anti-pyretic and analgesic without gastrophy

Wallace, John L., Cirino, Giuseppe, Del Soldato, Piero

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 166 KB

english, 1995

43

No-mesalamine (NCX-456) inhibits effector caspases and protects colonic epithelial cells from cytokine induced apoptosis

Stefano, Fiorucci, Luca, Santucci, Roberta, Mannucci, Piero, Del Soldato, Ildo, Nicoletti

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

44

Identification of muscarinic receptor subtype mediating colonic response to eating

Francesco Narducci, Gabrio Bassotti, Sergio Daniotti, Piero Del Soldato, Maria Antonia Pelli, Antonio Morelli

Journal:

Digestive Diseases and Sciences

Year:

1985

Language:

english

File:

PDF, 360 KB

english, 1985

45

Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation

Rajamanickam Baskar, Anna Sparatore, Piero Del Soldato, Philip Keith Moore

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

46

Reply to Savolainen: High Toxicity of Hydrogen Sulfide by the Inhibition of Mitochondrial Respiration

Lee, Moonhee, Soldato, Piero Del, Sparatore, Anna, McGeer, Patrick

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

47

Nitroaspirin plus clopidogrel versus aspirin plus clopidogrel against platelet thromboembolism and intimal thickening in mice

Momi, Stefania, Pitchford, Simon, Alberti, Paolo, Minuz, Pietro, Del Soldato, Piero, Gresele, Paolo

Journal:

Thrombosis and Haemostasis

Year:

2005

Language:

english

File:

PDF, 524 KB

english, 2005

48

Effect of nitric oxide-donating agents on human monocyte cyclooxygenase-2

Teresa Corazzi, Mario Leone, Rita Roberti, Piero Del Soldato, Paolo Gresele

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 236 KB

english, 2003

49

Effects of flurbiprofen and flurbinitroxybutylester on prostaglandin endoperoxide synthases

Giovanna Santini, Maria G. Sciulli, Maria R. Panara, Roberto Padovano, Maria di Giamberardino, Maria T. Rotondo, Piero Del Soldato, Paola Patrignani

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 836 KB

english, 1996

50

Effect of HCT1026, a nitric oxide (NO) releasing derivative of flurbiprofen on gastrointestinal mucosa: a double blind placebo-controlled endoscopic study

Fiorucci, Stefano, Santucci, Luca, Sardina, Marco, Santus, Giancarlo, Fransioni, Alberto, Soldatos, Piero Del, Morelli, Antonio

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 241 KB

english, 2003

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